Journal of Pediatric Case Reports

Cardiac Chloroma

Journal of Pediatric Case Reports

Published April 1, 2026

DOI: 10.37549/JPCR-25-0042

Abstract

Cardiac chloromas are rare extramedullary tumors associated with acute myelogenous leukemia that can infiltrate cardiac tissues, disrupt normal function, and contribute to heart failure. Their diagnosis is challenging due to their rarity and variable clinical presentation. Imaging techniques such as echocardiography, MRI, CT, and PET/CT are necessary for detecting these masses and assessing their extent. Histopathologic analysis confirms the diagnosis by identifying leukemic markers within the tumor. Systemic chemotherapy remains the primary treatment, but prognosis remains poor due to the aggressive nature of acute myeloid leukemia and the complexity of managing cardiac involvement.

Citation

Burstein WB, Towbin RB, Schaefer CM, Towbin AJ. Cardiac Chloroma. Journal of Pediatric Case Reports. 2026. doi:10.37549/JPCR-25-0042.

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