Journal of Pediatric Case Reports

Fontan-Associated Liver Disease

Journal of Pediatric Case Reports

Published November 1, 2025

DOI: 10.37549/JPCR-25-0027

Lucas J. Betts, BA1, Richard B. Towbin, MD2*, Carrie M. Schaefer, MD2, Alexander J. Towbin, MD3*

1 Creighton University School of Medicine, Omaha, Nebraska

2 Department of Radiology, Phoenix Children’s Hospital, Phoenix, Arizona

3 Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio

* Corresponding author: Richard B. Towbin (rtowbin@gmail.com)

Abstract

Fontan-associated liver disease (FALD) is a ubiquitous complication in patients with Fontan physiology. Optimal monitoring of FALD development typically starts with imaging. Liver stiffness values can help guide therapy and can act as a surrogate for disease severity. When nodules are present, they can be challenging. Looking for a lesion that behaves differently than other lesions is the best way to identify hepatocellular carcinoma.

Keywords: Abdomen, Liver, Vascular

Citation

Betts LJ, Towbin RB, Schaefer CM, Towbin AJ. Fontan-Associated Liver Disease. Journal of Pediatric Case Reports. 2025. doi:10.37549/JPCR-25-0027.

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