Hepatocellular Adenoma

Hepatic adenoma (HA) is a benign liver tumor that is rare, particularly in pediatric patients, where it is encountered most frequently in association with genetic conditions such as glycogen storage disease and has associated risks of hemorrhage, rupture, and malignant transformation. Lesions are often asymptomatic until rupture or hemorrhage and are detected by imaging, with MRI (or less favorably, multiphase contrast-enhanced CT) helpful to distinguish HA from other hepatic tumors with no potential for malignant transformation. A definitive diagnosis is with image-guided core needle biopsy. Management may include cessation of hormone therapy if applicable, serial imaging surveillance, screening for malignancy, and/or surgical resection, as well as transplantation in cases of adenomatosis, and embolization to control acute hemorrhage.