Journal of Pediatric Case Reports

Liposarcoma of the Lower Extremity

Journal of Pediatric Case Reports

Published October 28, 2025

DOI: 10.37549/JPCR-25-0029

Michael W. Stickels, BS1, Richard B. Towbin, MD2*, Douglas C. Rivard, DO3, Carrie M. Schaefer, MD2, Alexander J. Towbin, MD4*

1 University of Arizona College of Medicine, Phoenix Campus, Phoenix, Arizona

2 Department of Radiology, Phoenix Children’s Hospital, Phoenix, Arizona

3 Department of Radiology, Mercy Children’s Hospital, Kansas City, Missouri

4 Department of Radiology, Cincinnati Children’s Hospital and University of Cincinnati College of Medicine, Cincinnati, Ohio

* Corresponding author: Richard B. Towbin (rtowbin@gmail.com)

Abstract

Liposarcomas are the second most common soft-tissue tumor and primarily occur within the proximal lower extremity and the retroperitoneum. There are 5 different subtypes of tumor. While there are unique imaging features of each subtype, biopsy is required for diagnosis. Surgical excision remains the primary treatment option for all subtypes of lower extremity liposarcomas.

Keywords: musculoskeletal soft-tissue neoplasm

Citation

Stickels MW, Towbin RB, Rivard DC, Schaefer CM, Towbin AJ. Liposarcoma of the Lower Extremity. Journal of Pediatric Case Reports. 2025. doi:10.37549/JPCR-25-0029.

©Anderson Publishing, Ltd. All rights reserved. Reproduction in whole or part without express written permission is strictly prohibited.